Eccentric scientist Victor Von Frankenstein creates a grotesque creature in an unorthodox scientific experiment.

Famed monster slayer Gabriel Van Helsing is dispatched to Transylvania to assist the last of the Valerious bloodline in defeating Count Dracula. Anna Valerious reveals that Dracula has formed an unholy alliance with Dr. Frankenstein's monster and is hell-bent on exacting a centuries-old curse on her family.

On a dark and somber night, a secret cabal of monster hunters emerge from the shadows and gather at the foreboding Bloodstone Temple following the death of their leader. In a strange and macabre memorial to the leader’s life, the attendees are thrust into a mysterious and deadly competition for a powerful relic—a hunt that will ultimately bring them face to face with a dangerous monster.