Gru and Lucy and their girls—Margo, Edith and Agnes—welcome a new member to the Gru family, Gru Jr., who is intent on tormenting his dad. Gru also faces a new nemesis in Maxime Le Mal and his femme fatale girlfriend Valentina, forcing the family to go on the run.

John McClane is back and badder than ever, and this time he calls on the services of a young hacker in his bid to stop a ring of Internet terrorists intent on taking control of America's computer infrastructure.